Publications

Published peer-reviewed articles

These articles are relevant to the work at Nonagen Bioscience and are arranged in chronological order with the most recently published articles at the top. 

Furuya H, Sakatani T, Tanaka S, et al. Bladder cancer risk stratification with the Oncuria 10-plex bead-based urinalysis assay using three different Luminex xMAP instrumentation platforms. Res Sq [Preprint]. 2023 Nov 25:rs.3.rs-3635581. doi: 10.21203/rs.3.rs-3635581/v1. Update in: J Transl Med. 2024 Jan 2;22(1):8.

Murakami K, Furuya H, Hokutan K, et al. Association of SNPs in the PAI1 Gene with Disease Recurrence and Clinical Outcome in Bladder Cancer. Int J Mol Sci. 2023 Mar 3;24(5):4943. doi: 10.3390/ijms24054943.

Chen R, Pagano I, Sun Y, et al. A Diagnostic Gene Expression Signature for Bladder Cancer Can Stratify Cases into Prescribed Molecular Subtypes and Predict Outcome. Diagnostics (Basel). 2022 Jul 25;12(8):1801. doi: 10.3390/diagnostics12081801.

Murakami K, Pagano I, Furuya H, Daskivich T, Mori D, Rosser CJ. Clinical utility of Oncuria™, a multiplexed liquid biopsy for the noninvasive detection of bladder cancer-a pilot study. Diagnostics (Basel).2022;12(1):131. doi:10.3390/diagnostics12010131

Murakami K, Kamat AM, Dai Y, et al. Application of a multiplex urinalysis test for the prediction of intravesical BCG treatment response: a pilot study. Cancer Biomark. 2022;33(1):151-157. doi:10.3233/CBM-210221

Murakami K, Pagano I, Chen R, et al. Influencing factors on the Oncuria™ urinalysis assay: an experimental model. Diagnostics (Basel). 2021;11(6):1023. doi:10.3390/diagnostics11061023

Hirasawa Y, Pagano I, Chen R, et al. Diagnostic performance of Oncuria™, a urinalysis test for bladder cancer. J Transl Med. 2021;19(1):141. doi:10.1186/s12967-021-02796-4

Furuya H, Tabula L, Lee R, et al. Analytical validation of ONCURIA™ a multiplex bead-based immunoassay for the non-invasive bladder cancer detection. Pract Lab Med. 2020;22:e0018. doi:10.1016/j.plabm.2020.e00189

Furuya H, Chan OTM, Hokutan K, et al. Prognostic significance of lymphocyte infiltration and a stromal immunostaining of a bladder cancer associated diagnostic panel in urothelial carcinoma. Diagnostics (Basel). 2019;10(1):14. doi:10.3390/diagnostics10010014

Furuya H, Pagano I, Chee K, et al. Comparison of commercial ELISA kits, a prototype multiplex electrochemoluminescent assay, and a multiplex bead-based immunoassay for detecting a urine-based bladder-cancer-associated diagnostic signature. Diagnostics (Basel). 2019;9(4):166. doi:103390/diagnostic9040166

Masuda N, Ogawa O, Park M, et al. Meta-analysis of a 10-plex urine-based biomarker assay for the detection of bladder cancer. Oncotarget. 2018;9(6):7101-7111. doi:10.18632/oncotarget.2387

Goodison S, Ogawa O, Matsui Y, et al. A multiplex urinary immunoassay for bladder cancer detection: analysis of a Japanese cohort. J Transl Med. 2016;14(1):287. doi:10.1186/s12967-016-1043-1

Chan OTM, Furuya H, Pagano I, et al. Association of MMP-2, RB and PAI-1 with decreased recurrence-free survival and overall survival in bladder cancer patients. Oncotarget. 2017 Sep 6;8(59):99707-99721. doi: 10.18632/oncotarget.20686.

Huang S, Kou L, Furuya H, et al. A nomogram derived by combination of demographic and biomarker data improves the noninvasive evaluation of patients at risk for bladder cancer. Cancer Epidemiol Biomarkers Prev. 2016;25(9):1361-1366. doi:10.1158/1055-9965.EPI-16-0260.

Rosser CJ, Dai Y, Miyake M, et al. Simultaneous multi-analyte urinary protein assay for bladder cancer detection. BMC Biotechnol. 2014 Apr 1;14:24. doi: 10.1186/1472-6750-14-24.

Shimizu Y, Furuya H, Bryant Greenwood PB, et al. A multiplex immunoassay for the non-invasive detection of bladder cancer. J Transl Med. 2016;14:31. doi:10.1186/s12967-016-0783-2

Urquidi V, Netherton M, Gomes-Giacoia E, et al. A microRNA biomarker panel for the non-invasive detection of bladder cancer. Oncotarget. 2016;7(52):86290-86299. doi:10.18632/onc otarget.13382 

Chen LM, Chang M, Dai Y, et al. External validation of a multiplex urinary protein panel for the detection of bladder cancer in a multicenter cohort. Cancer Epidemiol Biomarkers Prev. 2014;23(9):1804-1812. doi:10.1158/1055-9965.EPI-14-0029.

Zhang G, Gomes-Giacoia E, Dai Y, et al. Validation and clinicopathologic associations of a urine-based bladder cancer biomarker signature. Diagn Pathol. 2014;9:200. doi:10.1186/s1300-014-0200-1

Miyake M, Lawton A, Dai Y, et al. Clinical implications in the shift of syndecan-1 expression from the cell membrane to the cytoplasm in bladder cancer. BMC Cancer. 2014 Feb 13;14:86. doi: 10.1186/1471-2407-14-86.

Miyake M, Ross S, Lawton A, et al. Investigation of CCL18 and A1AT as potential urinary biomarkers for bladder cancer detection. BMC Urol. 2013 Sep 5;13:42. doi: 10.1186/1471-2490-13-42.

Rosser CJ, Chang M, Dai Y, et al. Urinary protein biomarker panel for the detection of recurrent bladder cancer. Cancer Epidemiol Biomarkers Prev. 2014;23(7):1340-1345. doi:10.1158/1055-9965.EPI-14-0035.

Rosser CJ, Ross S, Chang M, et al. Multiplex protein signature for the detection of bladder cancer in voided urine samples. J Urol. 2013;190(6):2257-2262. doi:10.1016/j.juro.2013.06.011

Goodison S, Chang M, Dai Y, Urquidi V, Rosser CJ. A multi-analyte assay for the non-invasive detection of bladder cancer. PLoS One. 2012;7(10):e47469. doi:10.1371/journal.pone.0047469

Urquidi V, Goodison S, Cai Y, Sun Y, Rosser CJ. A candidate molecular biomarker panel for the detection of bladder cancer.  Cancer Epidemiol Biomarkers Prev. 2012;21(12):2149-2158. doi:10.1158/1055-9965.EPI-12-0428. 

Urquidi V, Goodison S, Kim J, et al. Vascular endothelial growth factor, carbonic anhydrase 9, and angiogenin as urinary biomarkers for bladder cancer detection. Urology. 2012 May;79(5):1185.e1-6. doi: 10.1016/j.urology.2012.01.016. Epub 2012 Mar 3.

Urquidi V, Goodison S, Ross S, et al. Diagnostic potential of urinary α1-antitrypsin and apolipoprotein E in the detection of bladder cancer. J Urol. 2012 Dec;188(6):2377-83. doi: 10.1016/j.juro.2012.07.094. Epub 2012 Oct 22.

Urquidi V, Chang M, Dai Y, et al. IL-8 as a urinary biomarker for the detection of bladder cancer. BMC Urol. 2012 May 4;12:12. doi: 10.1186/1471-2490-12-12.

Yang N, Feng S, Shedden K, et al. Urinary glycoprotein biomarker discovery for bladder cancer detection using LC/MS-MS and label-free quantification. Clin Cancer Res. 2011;17(10):3349-3359. doi:10.1158/1078-0432.CCR-10-3121

Rosser CJ, Liu L, Sun Y, et al. Bladder cancer-associated gene expression signatures identified by profiling of exfoliated urothelia. Cancer Epidemiol Biomarkers Prev. 2009;18(2):444-453. doi:10.1158/1055-9965.EPI-08-1002.

Kreunin P, Zhao J, Rosser C, Urquidi V, Lubman DM, Goodison S. Bladder cancer associated glycoprotein signatures revealed by urinary proteomic profiling. J Proteome Res. 2007;6(7):2631-2639. doi:10.1021/pr0700807